The Maria Baldwin House is a National Historic Landmark located at 196 Prospect Street, Cambridge, Massachusetts, United States. The house is the northern half of a 19th-century two-family house, notable for its associations with educator Maria Louise Baldwin (1856–1922). It was her home when she served as the first female African-American principal in a Massachusetts school at Cambridge's Agassiz Grammar School. As the schoolmaster, she supervised 12 teachers, all white, who presided over a 98% white student body. The Agassiz School has since been renamed the Maria Baldwin School in her honor. The Baldwin House was declared a National Historic Landmark in 1976.